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Author Topic: D N A  (Read 2401 times)

Offline space otter

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D N A
« on: March 15, 2018, 08:21:02 am »

we were having a good discussion in another thread but i think it needs it's own thread and reading this article i felt was a good place to start it..
i have also read about but have no actual proof that you can change your dna thru  different meditations..
that would be really interesting but if you have no base line you have no proof
sooo if anyone it trying it let me know..

here's the article


https://www.msn.com/en-us/news/technology/astronauts-dna-changed-by-time-in-space/ar-BBKdBPT?li=BBnb7Kz
Astronaut's DNA changed by time in space
 CNN CNN
By Susan Scutti, CNN
2 hrs ago

Spending a year in space not only changes your outlook, it transforms your genes.

Preliminary results from NASA's Twins Study
https://www.nasa.gov/feature/nasa-twins-study-confirms-preliminary-findings
reveal that 7% of astronaut Scott Kelly's genes did not return to normal after his return to Earth two years ago.
https://www.nasa.gov/press-release/nasa-astronaut-scott-kelly-returns-safely-to-earth-after-one-year-mission

The study looks at what happened to Kelly before, during and after he spent one year aboard the International Space Station through an extensive comparison with his identical twin, Mark, who remained on Earth.

NASA has learned that the formerly identical twins are no longer genetically the same.

Space genes'
The transformation of 7% of Scott's DNA suggests longer-term changes in genes related to at least five biological pathways and functions.

The newest preliminary results from this unique study of Scott, now retired from NASA, were released at the 2018 Investigator's Workshop for NASA's Human Research Program in January. Last year, NASA published its first round of preliminary results at the 2017 Investigator's Workshop. Overall, the 2018 findings corroborated those from 2017, with some additions.

To track physical changes caused by time in space, scientists measured Scott's metabolites (necessary for maintaining life), cytokines (secreted by immune system cells) and proteins (workhorses within each cell) before, during and after his mission. The researchers learned that spaceflight is associated with oxygen-deprivation stress, increased inflammation and dramatic nutrient shifts that affect gene expression.

In particular, Chris Mason of Weill Cornell Medicine reported on the activation of Scott's "space genes" while confirming the results of his separate NASA study, published last year.

To better understand the genetic dynamics of each twin, Mason and his team focused on chemical changes in RNA and DNA. Whole-genome sequencing revealed that each twin has more than expected unique mutations in his genome -- in fact, hundreds.

Although 93% of Scott's genetic expression returned to normal once he returned to Earth, a subset of several hundred "space genes" remained disrupted. Some of these mutations, found only after spaceflight, are thought to be caused by the stresses of space travel.

As genes turn on and off, change in the function of cells may occur.


© Robert Markowitz - NASA Expedition 45/46 Commander, Astronaut Scott Kelly along with his brother, former Astronaut Mark Kelly speak to news media outlets about Scott Kelly's 1-year mission aboard the…

Looking to Mars
Mason's work shows that one of the most important changes to Scott's cells was hypoxia, or a deficient amount of tissue oxygenation, probably due to a lack of oxygen and high levels of carbon dioxide. Possible damage to mitochondria, the "power plants of cells," also occurred in Scott's cells, as indicated by mitochondrial stress and increased levels of mitochondria in the blood.

Mason's team also saw changes in the length of Scott's telomeres, caps at the end of chromosomes that are considered a marker of biological aging. First, there was a significant increase in average length while he was in space, and then there was a decrease in length within about 48 hours of his landing on Earth that stabilized to nearly preflight levels. Scientists believe that these telomere changes, along with the DNA damage and DNA repair measured in Scott's cells, were caused by both radiation and calorie restrictions.

Additionally, the team found changes in Scott's collagen, blood clotting and bone formation due, most likely, to fluid shifts and zero gravity. The researchers discovered hyperactive immune activity as well, thought to be the result of his radically different environment: space.

The Twins Study helps NASA gain insight into what happens to the human body in space beyond the usual six-month International Space Station missions previously studied in other astronauts. Ten groups of researchers, including Mason's team, are looking at a wide variety of information about the Kelly twins' health, including how gut bacteria, bones and the immune system might be affected by living off planet.

Kelly's one-year mission is a scientific stepping stone to a planned three-year mission to Mars, NASA said. Research into how the human body adjusts to weightlessness, isolation, radiation and the stress of long-duration spaceflight is needed before astronauts are sent on journeys that would triple the time humans have spent in space so far.

CNN's Ashley Strickland contributed to this report.


ok Pim.. come back and add to this..i'm waiting to hear your info


Offline space otter

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Re: D N A
« Reply #1 on: March 16, 2018, 08:56:28 pm »
some very interesting stuff here but you'll have to go to the links to read it and if anyone wants to copy it to here great   - do it
 right now i'm just to lazy to go thru the motions..



This article is copyrighted by Global Freedom Movement. Visit our Re-post guidelines
https://globalfreedommovement.org/repost-guidelines/


Junk DNA: Your Hyperdimensional Doorway to Transformation (Part 1)

https://globalfreedommovement.org/junk-dna-your-hyperdimensional-doorway-to-transformation-part-1/



Junk DNA Part 2: NDEs, Sound, Evolution, and DNA Activation

https://globalfreedommovement.org/junk-dna-part-2-ndes-sound-evolution-and-dna-activation/


Offline space otter

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Re: D N A
« Reply #2 on: March 21, 2018, 03:09:19 pm »


interesting story of how dna found this woman's relatives...
more human interest than anything
a bit long


http://www.bbc.com/news/stories-43420678

Who were my parents - and why was I left on a hillside to die?
By Claire Bates
BBC Stories
19 March 2018

In the summer of 1937 a nine-month-old girl was hidden, with her hands tied, in a blackberry bush in southern England. She was found by sheer chance by a family of holidaymakers. Now 80, Anthea Ring has spent most of her life wondering why she was left to die and who her parents were. Thanks to a leap forward in genetic genealogy she finally has some answers.

rest of long article at link


Offline space otter

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Re: D N A
« Reply #3 on: August 05, 2019, 01:54:38 pm »


Quote
https://www.bbc.com/news/technology-48110894

I gave my DNA away. Can I get it back?
By Jane Wakefield
Technology reporter
4 August 2019

More and more people are doing DIY DNA tests

I recently spat in a pot and sent my saliva off in an envelope for analysis.

A growing number of people are willingly handing over their DNA to corporations in return for learning about their ancestry or to get health reports.

Why are we prepared to make this trade with our most intimate of data and what are we getting in return?

And what happens if you want your data back?

Interest in off-the-shelf DNA tests has exploded in recent years.
It is estimated that by the start of 2019, 26 million people had added their DNA to four leading databases, operated by Ancestry, 23andMe, MyHeritage and Gene by Gene.

In 2016, 23andme began selling access to anonymised data to more than 13 drug firms. Genentech reportedly paid $10m (£8.3m) to look at the genes of people with Parkinson's disease, while GlaxoSmithKline has reportedly paid $300m for access to the database.

The firm told the BBC that 80% of its customers choose to opt in to the research programme, and can opt out again at any time they choose.

Vagina cultures
But Tim Caulfield, research director at the health law institute at the University of Alberta, is not sure that people realise what they are signing up for when they answer the lengthy questionnaires about their health and heritage.

"People need to look carefully at privacy statements because often these firms are partnering with the pharmaceutical industry and people should be aware that is happening," he told the BBC.

And while most of the firms - including 23andMe - operate on the basis that users can withdraw consent to use their genetic information at any time, it can be more complicated than that.

"Once it has been aggregated and data is out there, it becomes difficult to get it back. And what happens if the firm goes bankrupt, what happens to all the DNA then?"

Bankruptcy is not the only thing that can go wrong.

Vice journalist Samantha Cole was concerned in May that the FBI may have confiscated her vaginal cultures when the DNA firm uBiome, which she had sent her sample to, was raided as part of an investigation into how the firm was billing for insurance.

And it is not the first time police have used the vast DNA databases which firms such as 23andme are amassing.

In April last year, it was revealed that US police uploaded DNA they suspected of belonging to a man thought to have committed multiple rapes, murders and burglaries across California, to GEDMatch, a free online database where anyone can share their genetic code in order to search for relatives who have also submitted theirs.

From this, police were able to create a complex family tree with the details of around 1,000 people, which led eventually to the third and fourth cousins of Joseph James DeAngelo, who was arrested and charged with the crimes.

None of those whose data was compiled had given prior consent for their data to be used in a murder enquiry.

Relative privacy
What happens when you take a genealogy test? Two BBC colleagues found out.
Dr Emiliano Cristofaro, head of the information security research group at University College London (UCL), said: "These firms like 23andMe and Ancestry DNA do the bare minimum to be GDPR-compliant (General Data Protection Regulation) but they don't always have the users' best interests at heart," he said.

"When we donate traditional data to companies it is our choice, but with genetic data your decision affects your close relatives as well. And we don't yet really know what this data contains. Every month we learn something new about genomic data and it might not be sensitive at the moment, but it might be in future."

The Christmas present that could tear your family apart
NHS to offer paid-for DNA tests if patients share data
Genetic testing: What secrets could it reveal about you?
Joyce Harper, a professor at UCL Institute for Women's Health, has used two of these databases to trace her family tree. But she questioned whether inputting information into a DNA database to "unlock relatives" was GDPR-compliant.

"Those that put their DNA in the bank have agreed to be in the database. They then build up their family tree with information about relatives who have not consented." she said.

She is also worried about data breaches, although she is not sure what damage hackers would do with DNA information.

Genome sequencing of the general population would improve the diagnosis and treatment of a whole range of diseases, but it also raises questions.

"Part of me is thinking 'just go with the flow' but we need to think about what it means to give away this data. Is your DNA then government property? I am not sure how much of an issue this could be."

Prof Harper recently visited just such a facility in China, and came away "with more questions than answers".

Mark Thomas, professor of evolutionary genetics at UCL, thinks there is some science behind the tests but the genetic information they share is often just too general to be of real value.

"What they mean by ancestry is that they have identified where some of your ancestors come from. If an Italian does the test, they will find that their ancestry is broadly Mediterranean and if someone from Africa does it, it will be broadly African.

"It can be useful if you want to join up with lost relatives, and if you are not going to take it too seriously and if sharing genetic data doesn't bother you."

Are the tests worth the data trade-off?
Tim Caulfield thinks the health information he was given was not particularly helpful.

"In the test I did, I was found to be at increased risk of colon cancer and my personalised health advice was to not smoke, exercise more and drink in moderation. I didn't need a genetic test to tell me that.

"These tests promise that this information will be empowering and will allow you to make adjustments to your life, but there is no evidence to back up the claim that people change their behaviour based on risk factor."
Does the mouth swab or saliva which people routinely post off for analysis actually reveal anything important?
23andMe told the BBC that one month after taking the test, half of respondents "were considering, planning, or had started to make changes to their dietary habits".

"We frequently hear from customers that seeing their results in black and white has motivated them to change their lifestyle. Behaviour change is not easy, but we're hopeful that we can continue to push the needle on this important topic," the firm said.

Doubts are also being raised about the accuracy of the heritage information shared by such tests.

In 2017, three identical triplets - Nicole, Erica and Jaclyn Dahm - had their DNA tested, with results revealed live on US TV. All had different results, one being told they had 11% French and German heritage, one 18% and another 22.3%

In response, 23andMe explained that there were different thresholds within the tests, one with 90% confidence levels and one with just 50% accuracy.

"In examining the triplets' breakdown that was shared with 23andMe in 2017, on the Conservative threshold, we found the Scandinavian ancestry was identical, and the European breakdowns are also quite similar, which is what we'd expect.

"The difference on the Speculative threshold are due to how our system is trained to label stretches of DNA at that confidence level. The system is essentially forced to make choices between two very similar regions of ancestry, instead of classifying them more generally as "Broadly European" or "Unassigned."


Related Topics
Data protectionGenetics

Offline space otter

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Re: D N A
« Reply #4 on: August 05, 2019, 02:07:22 pm »


https://www.msn.com/en-us/news/crime/signaling-a-new-era-man-caught-through-genetic-genealogy-gets-life-in-prison/ar-AAEPyIq?li=BBnb7Kz

Quote
Signaling a 'new era,' man caught through genetic genealogy gets life in prison
 7/25/2019

vid at link

In a milestone for forensic criminal investigators, a convicted killer received two life sentences on Wednesday for a 1987 double slaying after becoming the first person arrested through genetic genealogy to be found guilty at trial.
“The conviction and sentencing of William Earl Talbott II marks a new era for the use genetic genealogy for identifying violent criminals since it has now been tested and tried in a court of law,” geneology expert CeCe Moore told ABC News.

William Earl Talbott II was arrested in May 2018 and charged with aggravated murder for the Washington state cold case killings of 20-year-old Jay Cook and 18-year-old Tanya Van Cuylenborg, authorities said. A jury found Talbott guilty last month.

"By Talbott not pleading guilty, he's put a whole new generation of people through his horror," one of Cook's sisters, Laura Baanstra, said in court Wednesday. "Thank God Talbott is finally off the streets."

The young victims, from Canada, were traveling to Seattle by van when they were killed.

On November 24, 1987, Van Cuylenborg's partially-clothed body was found in a ditch in a wooded area, authorities said.


1/4 SLIDES © KOMO
William Talbott is sentenced in Everett, Wash., July 24, 2019.
Cook's body was discovered along a road two days later, authorities said.
Talbott led an "unremarkable life," one of Cook's sisters, Kelly Cook, said in court Wednesday.

The victims, "who essentially had everything to live for," Kelly Cook said, "would not have led unremarkable lives."

Decades went by without an arrest in the double slaying -- until Talbott was identified last year through genetic genealogy.

Genetic genealogy -- a novel technique that compares unknown DNA evidence to public genetic databases to identify suspects through their family members -- has been called a "game-changer" in the effort to crack cold case

In April 2018, the suspected "Golden State Killer" became the first public arrest through genetic genealogy. Since then about 70 suspects have been identified through the technology, according to Moore, who also appeared as an expert in ABC News "20/20" episodes.

While at least two men arrested through genetic genealogy have pleaded guilty in cold case killings, Talbott was the first of those arrested through genetic genealogy to stand trial, according to Moore.

Talbott was identified as a suspect when investigators took the unknown killer's DNA from the crime scene and uploaded it to a public genetic genealogy website. Promising matches were found for two of the unknown killer's relatives, authorities said, and once genealogists traced the suspect's family tree, they zeroed in on Talbott.

Investigators obtained a cup Talbott had used and tested the DNA, and found it matched the suspect DNA left at the crime scene, authorities said.

Talbott maintains his innocence, telling the court Wednesday, "I stand before you a man convicted of a crime that I did not commit."

...............................


https://abcnews.go.com/US/dj-admits-cold-case-murder-linked-dna-technique/story?id=60234009

DJ admits to cold case murder after being linked through novel DNA technique, apologizes to victim's family in court
By EMILY SHAPIRO Jan 8, 2019, 2:28 PM ET




https://abcnews.go.com/US/leave-murderer-running-streets-dna-databases-policy-changing/story?id=63150489

How a DNA database's new policy is changing police access and could hinder solving cold cases
By EMILY SHAPIRO May 22, 2019, 8:11 AM ET



https://abcnews.go.com/US/genetic-genealogy-links-marine-young-womans-murder-1976/story?id=63396410

Genetic genealogy links former Marine to young woman's murder in 1976: Sheriff
By EMILY SHAPIRO May 31, 2019, 11:20 AM ET
 


https://abcnews.go.com/US/maryland-man-nabbed-dna-genetic-genealogy-pleads-guilty/story?id=64083809

Maryland man nabbed through DNA, genetic genealogy pleads guilty to murder: Prosecutors
By EMILY SHAPIRO Jul 2, 2019, 12:10 PM ET
 



https://abcnews.go.com/US/90s-christopher-tapp-convicted-rape-murder-today-set/story?id=64339196&cid=clicksource_4380645_null_card_image

'A new beginning': Man convicted of murder in the '90s exonerated thanks to genetic genealogy
By EMILY SHAPIRO Jul 17, 2019, 4:32 PM ET
 

 

Offline The Seeker

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Re: D N A
« Reply #5 on: August 05, 2019, 07:07:26 pm »
 ::) Willingly giving up a DNA sample for what amounts to vanity and nothing else does not make any sense to me, and it will be used against you in any way possible...

Nope.

 ::)

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Offline Shasta56

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Re: D N A
« Reply #6 on: August 08, 2019, 03:24:44 pm »
I've seen the commercials that are meant to be so appealing.  I've also seen the warnings about insurance companies using the information to deny coverage.  I've had fun researching my family tree.  That's quite sufficient.
Daughter of Sekhmet

 


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